This comprehensive guide is designed to equip researchers with in-depth knowledge of patch-clamp techniques, their applications, and experimental protocols. 

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Whether you are an experienced scientist, a new researcher just starting to work with methodologies in patch-clamp electrophysiology, or a mentor looking for an excellent teaching and training resource, you will find this manual an invaluable tool in your lab.

Advance your Research in Electrophysiology 

As researchers and through numerous collaborations with fellow scientists in neuroscience and cellular biology, we possess extensive expertise in preparing acute brain slices for patch-clamp electrophysiology, fully appreciating the power of this method.

This guide reflects this expertise and aims to provide researchers with a comprehensive understanding of patch-clamp techniques, applications and experimental protocols. 



Explore What's Inside Precisionary's  Acute Brain Slice Experimental Research Manual

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Precisionary’s vibrating microtomes, innovative design and engineering, space-saving ergonomics, and state-of-the-art automation bring greater speed, precision, and consistency to your experiments. All of them.
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Acute Brain Slice

 Free Step-By-Step Guide

Have technical questions, need trouble-shooting help, or require a customized solution? Our scientific experts are here to help!

The most precise & consistent sectioning tools in the world for patch-clamp electrophysiology.

Achieve research images like these with guidance from the slicing experts at Precisionary

Precision-Cut Lung Slice immunostained against Collagen 1a1.
Acute brain slice showing Purkinje cells expressing GCaMP6f, ideal for calcium imaging and functional studies
Time-lapse image showing circadian cycling of neurons in the SCN from a PER2::luciferase mouse.
Healthy acute mouse brain slice of the hippocampal region, displaying abundant neurons ideal for patch-clamp electrophysiology.

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